Ethical deficit is research asset for Chinese stem cell science

stem cells In five to ten years China could become a world leader in therapeutic cloning and related research, a US stem cell scientist has predicted in the journal Nature. Xiangzhong Yang, of the University of Connecticut, contends that China's main asset is that it lacks the ethical qualms which have hampered the development of research on human embryos in Western countries. "In addition," he says, "the relatively easy access to human material, including embryonic and foetal tissues, in China is a huge advantage for researchers".

Chinese scientists have already achieved notable progress towards… MORE





Australian clinic creates two “saviour siblings”

Tasmanian couple Leanne and Stephen with their 4-year-old son An IVF clinic has claimed an Australian first by achieving two pregnancies of "saviour siblings". Sydney IVF said that it had culled embryos for tissue compatibility so that they could provide "spare parts" for a sick sibling. When their child is born, a Tasmanian couple will be able to treat a 4-year-old son who suffers from a rare condition called hyper IgM syndrome. Another couple will be able to treat a child with leukaemia. Although other IVF clinics have created "designer babies" which are free… MORE




Leading US cancer institute “withheld risks” of experiment

Dr E. Donnall Thomas A court case involving one of America's leading medical research centres has opened up a discussion of the limits of informed consent. The Fred Hutchinson Cancer Research Center in Seattle and three of its researchers are disputing allegations that they misled participants in an experiment which ran from 1983 to 1991. The defendants include Dr E. Donnall Thomas, who won the 1990 Nobel Prize for his pioneering work in bone marrow transplants.

At the heart of the complex case is whether the patients understood what they had agreed to. "The… MORE





“Parachute research” for drug companies hits ethical nerve

Drug companies and ethicists in the US are troubled by the ethical dilemmas of conducting clinical trials overseas. A report in the New York Times says that American companies are increasingly turning to former Soviet bloc countries with good, but underpaid doctors and compliant patients where they can carry out their trials more cheaply. Because there are often no government subsidies for prescription drugs in these countries, few people can afford to buy them. Participating in a clinical trial can be a patient's best chance for effective medication.

But what happens when the trials finish? Do the companies take special… MORE





Sacked scientist campaigns for unbiases US science policy

A scientist sacked from the President's Council on Bioethics and a serving member of the Council have published a sharp critique of George Bush's science policy. Writing in the journal PLoS Biology, Elizabeth Blackburn, an Australian, and Janet Rowley, both biologists, have complained that the Council's recent reports underestimated the therapeutic potential of embryonic stem cell research and distorted the motivations of scientists studying ageing. "There is always this strong implication [in the reports] that medical research is not what God intended, that there is something unnatural about it," Dr Blackburn told the Boston Globe. "We had a great many… MORE




Menopause dogma could be a myth

Defying half a century of conventional wisdom, scientists have discovered that female mammals can produce new eggs after birth. Until now it had always been thought that females were born with a limited number of eggs which are depleted with age.

But research on mice at the Massachusetts General Hospital in Boston has shown that new follicles, the tiny sacs in which eggs grow, are being created well into adult life from stem cells. "These are basic biological findings that may change everything in our field" says Dr Jonathan Tilly. "Although there is no way to say how long it… MORE





Save me from my doctors, says UK patient

A 44-year-old man with a degenerative brain condition has challenged official UK guidelines on withdrawing life-prolonging treatment. As a victim of cerebellar ataxia, Leslie Burke is already confined to a wheelchair and foresees that he will eventually be paralysed and unable to communicate even though he will be mentally competent. He fears that under General Medical Council guidelines his doctors could withhold food and water from him until he died.

Mr Burke's barrister argues that the guidelines could breach his right to life and his right to be spared inhuman and degrading treatment under the European convention on human rights,… MORE





Watching the watchdog

The UK bodies which regulate nurses and doctors have been hauled before the High Court for excessive leniency in two recent cases. A new government body, the Council for Regulation of Healthcare Professionals, has challenged a mere caution given to a nurse who ogled pornographic websites while at work in a children's ward and the acquittal of a doctor who had an inappropriate relationship with a patient. The Council was established last year to deal with extreme cases where the public interest in having a "clearly perverse" decision overturned outweighs the public interest in independent self-regulation. This is the first… MORE




IN BRIEF: Israeli surprise; Vatican appointment; Singapore sperm shortage; Australian IVF; stem cell

A scientist who tried to poison his wife and covered up his crime by lacing products on supermarket shelves with poison is teaching medical ethics at the University of Manchester in the UK. Paul Agutter, 57, was released from jail in 2002 after serving 7 years of a 12-year sentence. A few weeks ago he was engaged to teach philosophy and medical ethics for two hours a week at night school. MORE




Harvard scientists offer 17 stem cell lines for free

Douglas Melton Exasperated with US restrictions on embryonic stem cell research, one of the leading experts in the field, Douglas Melton, of Harvard University, and his colleagues have created 17 stem cell lines which they plan to give away to other laboratories. Melton says that the 17 lines were created with private funding from 344 IVF embryos which had developed for 3 to 5 days. He has also written a "cookbook" to help other scientists use his stem cells and create more lines.

In recent weeks restrictions imposed by President Bust, which allow federal… MORE




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