July
04
  2:56:01 AM

VIVE LA 1% DIFF?RENCE?

The fact that there is only a about a 1% difference between the genetic make-up of chimpanzees and human has been called "the most overly exposed factoid in modern science". First established in a paper in 1975, it was confirmed a couple of years ago by the Chimpanzee Sequencing and Analysis Consortium. However, a feature in the journal Science points out that this figure has enormous limitations. "For many, many years, the 1% difference served us well because it was under-appreciated how similar we were," says Pascal Gagneau, a zoologist at the University of California, San Diego. "Now it's totally clear that it's more a hindrance for understanding than a help."

The consortium pointed out that many stretches of DNA have been inserted or deleted in the genes. They account for an additional 3% difference. Entire genes are often reduplicated or lost, further distinguishing chimps from humans. Recent research shows that human and chimpanzee gene copy numbers differ by 6.4%.

Is it possible to propose a precise figure for the difference between the two species? Probably not, scientists feel. "I don't think there's any way to calculate a number," says Svante P??bo, a member of the consortium working in Germany. "In the end, it's a political and social and cultural thing about how we see our differences."


 

 Search BioEdge

 Subscribe to BioEdge newsletter
rss Subscribe to BioEdge RSS feed

 Best of the web

 Recent Posts
Indian surrogate for US woman dies in Gurjarat
18 May 2012
Do reproductive rights survive gender reassignment?
19 May 2012
South African activists begin euthanasia campaign
19 May 2012
70 assisted suicides in Washington state in 2011
19 May 2012
Would-be grandparents pay for their daughters’ egg freezing
19 May 2012

 Tags
organ trafficking, stem cells, bioethics, euthanasia, assisted suicide, surrogacy, Australia, commercialization, IVF, Canada, US, genetic testing, embryonic stem cells, Down syndrome, UK, suicide, organ transplants, sperm donation, organ donation, informed consent, India, sex selection, research, Netherlands, neuroscience, clinical trials, human drama, law, China, abortion,