Faced with a shortage of kidneys, surgeons
are resorting to transplanting cancerous kidneys into desperately ill
patients. Body parts from the elderly and patients with a history of
cancer or drug abuse are being used. In the UK, the use of high-risk
donors has doubled in ten years: from 13% to 26% per cent of
transplants.
Professor James Neuberger, medical director
of NHS Blood and Transplant told the UK’s Daily Mail: "There is no
doubt that if we had more donors, we could be a lot more selective
about those used. In some cases this is completely safe but we're
seeing organs from higher risk donors used in order to meet the growing
need for transplantation." But the alternative, he said, is death on a
waiting list.
The problem is that potential donors are
fatter and more diseased. Furthermore, the immunosuppressant drugs
which patients take after surgery to reduce the chance of rejection
increase the chance of the cancer recurring.
In an article in the British Journal of Urology International,
a team from the University of Maryland described five transplanted
kidneys with cancer masses. These were cut out before being transferred
into the recipient. The researchers concluded that such donations
"offer a minor, yet feasible, solution to the current organ shortage."
Serious ethical issues are involved here.
Are the patients aware of the risks that they are taking? Who should
have the final say, the patient, or the doctor? Although all the
patients in the American study were aware of the risk they were taking,
the experience of a man in the UK shows that this is not always the
case.
A 37-year-old chef, John Richardson,
received a new heart, but died five days later without regaining
consciousness. His wife was shocked to learn afterwards that the donor
had hanged himself, was a smoker with several tattoos - creating a risk
of hepatitis - and a cocaine user. It had taken 15 minutes to restart
his heart when he was found. Furthermore, the heart had a hole in it
and needed repair before transplant.
From the surgeon’s point of view, complete
transparency might not always be in the patient’s interest. Time may be
limited, the risk may be hard to assess and patients might be too
choosy.
As one British surgeon told the BBC: "It is
fair to say that whilst patient choice is championed in many other
areas of healthcare, it's difficult to reconcile that patient choice
with running an efficient transplant service." ~ Practical Ethics, Dec 9; BBC, Dec 7; BBC, Nov 24; Daily Mail, Nov 25